The nuclear receptor 4A family members: mediators in human disease and autophagy

The nuclear receptor 4A family members: mediators in human disease and autophagy

Blog Article

Abstract The Nuclear receptor 4A (NR4A) subfamily, which belongs to the nuclear receptor (NR) superfamily, has Body Weight Scales three members: NR4A1 (Nur77), NR4A2 (Nurr1) and NR4A3 (Nor1).They are gene regulators with broad involvement in various signaling pathways and human disease responses, including autophagy.Here, we provide a concise overview of the current understanding of the role of the NR4A subfamily members in human diseases and review the research into their regulation of Pet Medical Tape cell autophagy.

A deeper understanding of these mechanisms has potential to improve drug development processes and disease therapy.